1. in view of the fact that something else is owed or has been pledged
    ExamplesCan I have an advance against next month's salary? • The bank advanced him £10,000 against the security of his house.
  2. compared with

"...investment can be written off against the marginal rate of tax" [Investors Chronicle]

Use against in a sentence

The employee wanted to ask about his draw account and then ask if he could have an advance against next months salary.

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I was firmly against his belief that reality was objective because the double slit experiment completely contradicted that long held idea.

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My brother was facing hard times after his wife left him, so he went to his bank to ask them if he could borrow against his home equity to pay for his lawyers.

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death-backed bonds hedged tender